- Famotidine is a histamine-2 blocker. It works by decreasing the amount of acid the stomach produces.
- Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.
- Famotidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.
- Famotidine may also be used for purposes not listed in this medication guide.